| 1. | The major route of metabolism is by its target enzymes via cholinesterase-mediated hydrolysis.
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| 2. | The ANSM committee also requested data on non-target enzyme affinity from the manufacturer Bial.
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| 3. | The target enzyme in HIV cannot distinguish the difference, but human enzymes can, he said.
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| 4. | The kinase then phosphorylates target enzymes, regulating their activities.
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| 5. | More research is needed to identify inhibitors that selectively target enzymes in the glyoxylate cycle.
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| 6. | Some reversible inhibitors bind so tightly to their target enzyme that they are essentially irreversible.
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| 7. | Mevastatin was demonstrated to be an unusually potent inhibitor of the target enzyme and of cholesterol biosynthesis.
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| 8. | The "'mannose 6-phosphate receptors ( MPRs ) "'are transmembrane glycoproteins that target enzymes to lysosomes in vertebrates.
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| 9. | In drug design it is important to consider the concentrations of substrates to which the target enzymes are exposed.
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| 10. | A homotropic allosteric modulator is a substrate for its target enzyme, as well as a regulatory molecule of the enzyme's activity.
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